Mitochondria restrict growth of the intracellular parasite Toxoplasma by limiting its uptake of fatty acids. Pernas, L., Bean, C., Boothroyd, J.C., and Scorrano, L. (2018) Cell Metabolism
Selected for preview: Fighting for Resources: Who Started the Battle? Who Is Winning It? Zuzarte-Luis, V. and Mota M.M. (2018) Cell Metabolism
A Toxoplasma gondii locus required for the direct manipulation of host mitochondria has maintained multiple ancestral functions. Blank, M.L., Parker, M.L., Ramaswamy, R., Powell, C.J., English, E.D., Adomako-Ankomay, Y., Pernas, L., Workman, S.D., Boothroyd, J.C., Boulanger, M.J., and Boyle, J.P. (2018) Molecular Microbiology
Gene duplication-driven evolution of a novel trait in Toxoplasma gondii and its near relatives. Adomako-Ankomah, Y., English, E.D., Danielson, J.J., Pernas, L., and Boyle, J.P. (2016) PLoS Genetics
Toxoplasma effector MAF1 mediates recruitment of host mitochondria and impacts the host response.
Pernas, L., Adomako-Ankomah, Y., Shastri, A.J., Ewald, S.E., Treeck M, Boyle, J.P., and Boothroyd, J.C. (2014) PLoS Biology
Selected for synopsis: MAF1 sequesters mitochondria for Toxoplasma gondii.
Sedwick, C (2014) PLoS Biology, F1000 Prime Article
Immune-profiling of pregnant Toxoplasma-infected US and Colombia patients reveals surprising impacts of infection on peripheral blood cytokines. Pernas, L., Ramirez, R., Holmes, T.H., Montoya, J.G., and Boothroyd, J.C. (2014) Journal of Infectious Diseases
Association of host mitochondria with the parasitophorous vacuole during Toxoplasma infection is not dependent on rhoptry proteins ROP2/8. Pernas, L. and Boothroyd, J.C. (2010) International Journal of Parasitology
Reviews & Commentary
RevAMPing Mitochondrial Shape to Live Longer. Pernas, L. and Scorrano, L. (2017) Cell Metabolism
Mito-Morphosis: Mitochondrial fusion, fission, and cristae remodeling as key mediators of cellular function. Pernas, L. and Scorrano, L. (2016) Annual Reviews of Physiology